N-乙氧羰基邻苯二甲酰亚胺合成路线 （共 86 条）
反应条件
sodium carbonate in water
6 h;
参考文献
Itoh; Kori; Inada; Nishikawa; Kawamatsu; Sugihara
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2078 - 2089
参考文献
Heller; Jacobsohn
Chemische Berichte, 1921 , vol. 54, p. 1115
参考文献
Heller; Jacobsohn
Chemische Berichte, 1921 , vol. 54, p. 1115
反应条件
sodium carbonate in water
T=20°C;
参考文献
Levit, Galina L.; Gruzdev, Dmitry A.; Krasnov, Victor P.; Chulakov, Evgeny N.; Sadretdinova, Liliya Sh.; Ezhikova, Marina A.; Kodess, Mikhail I.; Charushin, Valery N.
Tetrahedron Asymmetry, 2011 , vol. 22, # 2 p. 185 - 189
反应条件
potassium carbonate in water
参考文献
Allelix Biopharmaceuticals Inc.
Patent: US5770742 A1, 1998 ;
US 5770742 A
反应条件
sodium hydrogencarbonate in tetrahydrofuran
8 h;
参考文献
Barf; De Boer; Wikstrom; Peroutka; Svensson; Ennis; Ghazal; McGuire; Smith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 24 p. 4717 - 4726
反应条件
sodium carbonate in chloroform; water
T=25°C; 2 h;
参考文献
Sato, Yasuhiko; Nakai, Hideo; Wada, Masao; Mizoguchi, Tomishige; Hatanaka, Yasumaru; et al.
Liebigs Annalen der Chemie, 1985 , # 6 p. 1099 - 1118
反应条件
sodium carbonate in water
T=20°C; 2 h;
参考文献
Schering Corporation; Pharmacopeia Drug Discovery, Inc.
Patent: EP1140909 B1, 2005 ;
Location in patent: Page/Page column 73 ;
反应条件
sodium carbonate in water
1.16667 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2005/21519 A2, 2005 ;
Location in patent: Page/Page column 36 ;
WO 2005/021519 A2
反应条件
1.1: sodium carbonate / water / 2 h / 20 °C
1.2: 0.33 h / Reflux
2.1: potassium carbonate / water; acetone / 24 h / Inert atmosphere; Irradiation
View Scheme
参考文献
Griesbeck, Axel G.; Neudoerfl, Joerg; Kiff, Alan De
Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 518 - 524
