3,4-二甲氧基苯丙炔酸合成路线 (共 18 条)
参考文献
Perkin; Schiess
Journal of the Chemical Society, 1904 , vol. 85, p. 162
反应条件
caesium carbonate in N,N-dimethyl-formamide T=60°C; P=760.051 Torr; 14 h; Reagent/catalystSolvent;
参考文献
Aher, Ravindra D.; Gade, Madhuri H.; Reddy, R. Santhosh; Sudalai, Arumugam
Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical and Analytical Chemistry, 2012 , vol. 51, # 9-10 p. 1325 - 1329,5
反应条件
1: With lithium hydroxide hydrate in tetrahydrofuran; methanol; water T=20°C; 2: With hydrogenchloride in water; ethyl acetate T=0°C; pH=4; 1 h;
参考文献
Hajbi, Youssef; Neagoie, Cleopatra; Biannic, Berenger; Chilloux, Aurelie; Vedrenne, Emeline; Baldeyrou, Brigitte; Bailly, Christian; Merour, Jean-Yves; Rosca, Sorin; Routier, Sylvain; Lansiaux, Amelie
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 11 p. 5428 - 5437
反应条件
1: Br2 / CH2Cl2 / 0 °C 2: KOH / ethanol / 4 h / Heating View Scheme
参考文献
Lee; Tseng
Synthesis, 2001 , # 15 p. 2247 - 2254
反应条件
1: SOCl2 / 4 h / Heating 2: Br2 / CH2Cl2 / 0 °C 3: KOH / ethanol / 4 h / Heating View Scheme
参考文献
Lee; Tseng
Synthesis, 2001 , # 15 p. 2247 - 2254
反应条件
1: thionyl chloride / 4 h / Reflux 2: bromine / dichloromethane / 0.33 h / 0 °C 3: potassium hydroxide / ethanol / 6 h / Reflux View Scheme
参考文献
Sun, Jie; Ding, Wei-Xian; Hong, Xiao-Ping; Zhang, Ke-Yun; Zou, Yong
Chemistry of Natural Compounds, 2012 , vol. 48, # 1 p. 16 - 22
反应条件
1: bromine / dichloromethane / 0.33 h / 0 °C 2: potassium hydroxide / ethanol / 6 h / Reflux View Scheme
参考文献
Sun, Jie; Ding, Wei-Xian; Hong, Xiao-Ping; Zhang, Ke-Yun; Zou, Yong
Chemistry of Natural Compounds, 2012 , vol. 48, # 1 p. 16 - 22
反应条件
potassium hydroxide in ethanol 6 h; Reflux;
参考文献
Sun, Jie; Ding, Wei-Xian; Hong, Xiao-Ping; Zhang, Ke-Yun; Zou, Yong
Chemistry of Natural Compounds, 2012 , vol. 48, # 1 p. 16 - 22
参考文献
Fulton; Robinson
Journal of the Chemical Society, 1933 , p. 1463,1464
反应条件
hydrogen; Lindlar's catalyst in ethanol
参考文献
Adler,E.; Gustafsson,B.
Acta Chemica Scandinavica (1947-1973), 1963 , vol. 17, p. 27 - 36