4-(4-氯苯基)-2-吡咯烷酮合成路线 （共 17 条）
反应条件
1: 82 percent / , Zn-Cu, POCl3 / diethyl ether / 20 h / Ambient temperature 2: 93 percent / Zn / acetic acid / 14 h / Ambient temperature 3: 42 percent / hydroxylamine-O-sulphonic acid, formic acid / 10 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 27, # 14 p. 2455 - 2465
反应条件
1: 93 percent / Zn / acetic acid / 14 h / Ambient temperature 2: 42 percent / hydroxylamine-O-sulphonic acid, formic acid / 10 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 27, # 14 p. 2455 - 2465
反应条件
1: 65 percent / 1 M NH4OH / 1 h / 70 °C 2: 59 percent / H2, Raney nickel W-5 / ethanol / 16 h / 3040 Torr / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 34, # 12 p. 2641 - 2645
反应条件
1: 16 percent / NH3 / tetrahydrofuran / 3 h 2: 65 percent / 1 M NH4OH / 1 h / 70 °C 3: 59 percent / H2, Raney nickel W-5 / ethanol / 16 h / 3040 Torr / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 34, # 12 p. 2641 - 2645
反应条件
1.1: N,N,N',N'-tetramethylguanidine / 72 h / 20 °C 2.1: acetic acid; iron / 1.5 h / Reflux 2.2: Cooling with ice View Scheme
反应条件
hydrogenchloride; water in water 16 h; Reflux;
参考文献
Biswas, Kallolmay; Gholap, Rajesh; Srinivas, Padakanti; Kanyal, Sachin; Sarma, Koushik Das
RSC Advances, 2014 , vol. 4, # 5 p. 2538 - 2545
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Heating;
参考文献
Wall; Baker
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1340 - 1348
