4-氨基-4'-(N,N-二甲氨基)二苯乙烯合成路线 （共 9 条）
反应条件
ammonia; iron(II) sulfate in ethanol; water 2 h; Heating;
参考文献
Harder; Wessig; Bendig; Stoesser
Journal of the American Chemical Society, 1999 , vol. 121, # 28 p. 6580 - 6588
反应条件
1: 85 percent / piperidine / 2 h / 140 °C 2: 68 percent / FeSO4*7H2O, NH3 / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 28 p. 6580 - 6588
反应条件
1: 85 percent / piperidine / 2 h / 140 °C 2: 68 percent / FeSO4*7H2O, NH3 / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 28 p. 6580 - 6588
反应条件
1: NaH / dimethylformamide 2: SnCl2 / H2O; ethanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 3 p. 719 - 726
反应条件
1: Heating 2: NaH / dimethylformamide 3: SnCl2 / H2O; ethanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 3 p. 719 - 726
反应条件
1.1: phosphorus tribromide; pyridine / 0 °C 2.1: 120 °C 3.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 °C / |Inert atmosphere 3.2: 12 h / 20 °C / |Inert atmosphere 4.1: tin(ll) chloride / ethyl acetate / 4 h / 90 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 14 p. 5843 - 5859
反应条件
1.1: sodium tetrahydroborate / methanol / 0 °C 2.1: phosphorus tribromide; pyridine / 0 °C 3.1: 120 °C 4.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 °C / |Inert atmosphere 4.2: 12 h / 20 °C / |Inert atmosphere 5.1: tin(ll) chloride / ethyl acetate / 4 h / 90 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 14 p. 5843 - 5859
反应条件
1: 5 h / 140 °C 2: sodium hydride / tetrahydrofuran / 0.5 h / 50 °C / |Inert atmosphere 3: hydrogenchloride; SnCl2·2H2O / ethanol; water / 7 h / 20 °C / |Reflux View Scheme
参考文献
Journal of Physical Organic Chemistry, , vol. 25, # 12 p. 1343 - 1350
反应条件
1: NaOCH3 / N,N-dimethyl-formamide; ethanol 2: NaOH; stannous chloride / ethyl acetate; ethanol View Scheme
