[(1R,3S)-3-羟基环戊基]氨基甲酸叔丁酯合成路线 （共 3 条）
反应条件
triethylamine in dichloromethane T=0 - 20°C;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2009/23269 A2, 2009 ;
Location in patent: Page/Page column 42 ;
WO 2009/023269 A2
反应条件
1: vinyl acetate; (1R,4S)-4-Azido-cyclopent-2-enol With Pancreatin in tetrahydrofuran Acetylation; 3 h; 2: di-tert-butyl dicarbonate With hydrogen; palladium on activated charcoal in ethyl acetate reductive acylation; P=3102.89 Torr; Title compound not separated from byproducts;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 17 p. 1917 - 1920
反应条件
Dess-Martin periodane in dichloromethane
T=0 - 20°C;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2009/23269 A2, 2009 ;
Location in patent: Page/Page column 42-43 ;
WO 2009/023269 A2
