2-(吡啶-3-基)苯甲酸乙酯合成路线 (共 5 条)
反应条件
potassium carbonate; tetrakis in toluene 3 h; Heating / reflux;
参考文献
MERCK and CO., INC.
Patent: WO2008/10964 A1, 2008 ;
Location in patent: Page/Page column 154 ;
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water 48 h; Heating;
参考文献
Rebstock, Anne-Sophie; Mongin, Florence; Trecourt, Francois; Queguiner, Guy
Tetrahedron, 2003 , vol. 59, # 27 p. 4973 - 4977
反应条件
tetrakis(triphenylphosphine) palladium(0); 2,2,6,6-tetramethylpiperidinyl-lithium; (tBu)2Zn 1.) THF, RT, 2.) THF, RT, 24 h; Yield givenMultistep reaction;
参考文献
Kondo, Yoshinori; Shilai, Manabu; Uchiyama, Masanobu; Sakamoto, Takao
Journal of the American Chemical Society, 1999 , vol. 121, # 14 p. 3539 - 3540
反应条件
sodium hydroxide in ethanol 18 h; Heating;
参考文献
Rebstock, Anne-Sophie; Mongin, Florence; Trecourt, Francois; Queguiner, Guy
Tetrahedron, 2003 , vol. 59, # 27 p. 4973 - 4977
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran
T=0°C; 2 h;
参考文献
Tilly, David; Castanet, Anne-Sophie; Mortier, Jacques
Tetrahedron Letters, 2006 , vol. 47, # 7 p. 1121 - 1123