N-叔丁氧羰基-生物素基乙二胺合成路线 （共 3 条）
反应条件
N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide in methanol; acetonitrile T=20°C; 5 h;
参考文献
Bioorganic and medicinal chemistry, , vol. 11, # 2 p. 235 - 249
反应条件
1: 100 percent / CHCl3 / 16 h / 20 °C 2: 56 percent / EDC / methanol; acetonitrile / 5 h / 20 °C View Scheme
参考文献
Bioorganic and medicinal chemistry, , vol. 11, # 2 p. 235 - 249
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 1 h;
参考文献
Zhuang, Yu-De; Chiang, Po-Yi; Wang, Chia-Wen; Tan, Kui-Thong
Angewandte Chemie - International Edition, 2013 , vol. 52, # 31 p. 8124 - 8128
Angew. Chem., 2013 , vol. 125, # 31 p. 8282 - 8286
