(2R)-氨基(2-氯苯基)乙酸盐酸盐(1:1)合成路线 （共 4 条）
反应条件
1.1: sulfuric acid / 5 h / 0 °C / |Reflux 2.1: acetonitrile; ethyl acetate / 0.25 h / 25 - 30 °C 2.2: |Reflux View Scheme
参考文献
Sashikanth, Suthrapu; Raju, Veeramalla; Somaiah, Sripathi; Rao, Peddisrinivasa; Reddy, Karnativenugopal
Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-N0828-OP, p. 621 - 624
反应条件
sulfuric acid T=0°C; 5 h; Reflux;
参考文献
Sashikanth, Suthrapu; Raju, Veeramalla; Somaiah, Sripathi; Rao, Peddisrinivasa; Reddy, Karnativenugopal
Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-N0828-OP, p. 621 - 624
反应条件
1.1: sulfuric acid / 5 h / 0 °C / |Reflux 2.1: acetonitrile; ethyl acetate / 0.25 h / 25 - 30 °C 2.2: |Reflux 3.1: sulfuric acid / water; acetone / 7.5 h View Scheme
参考文献
Sashikanth, Suthrapu; Raju, Veeramalla; Somaiah, Sripathi; Rao, Peddisrinivasa; Reddy, Karnativenugopal
Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-N0828-OP, p. 621 - 624
反应条件
Multi-step reaction with 2 steps 1: methanol; water / 16 h / 25 - 30 °C2: water; hydrogenchloride / diethyl ether / 4 h / 90 °C
参考文献
Sashikanth, Suthrapu; Raju, Veeramalla; Somaiah, Sripathi; Rao, Peddisrinivasa; Reddy, Karnativenugopal Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-N0828-OP, p. 621 - 624
