2-(2,4-二羟基苯基)-2H-苯并噻唑合成路线 (共 13 条)
反应条件
1: 92 percent / thiourea dioxide, 4N NaOH / ethanol / 80 °C
2: 91 percent / BBr3 / CH2Cl2 / 2 h / Ambient temperature
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参考文献
Rosevear, Judi; Wilshire, John F. K.
Australian Journal of Chemistry, 1987 , vol. 40, # 10 p. 1663 - 1673
反应条件
1: 88 percent / thiourea dioxide, 4N NaOH / ethanol / 80 °C
2: 75 percent / BBr3 / CH2Cl2 / 72 h / Ambient temperature
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参考文献
Rosevear, Judi; Wilshire, John F. K.
Australian Journal of Chemistry, 1987 , vol. 40, # 10 p. 1663 - 1673
反应条件
1: NaNO2 / H2O / 1 h / 0 - 5 °C
2: ethanol; H2O / 2 h / Ambient temperature
3: 40percent NaOH aq., Zn powder / 72 h / Ambient temperature
View Scheme
参考文献
Li,S.; Albertsson,A.; Gupta,A.
Monatshefte fuer Chemie, 1984 , vol. 115, p. 853