3-溴甲基-3-羟甲基-1-氧杂环丁烷合成路线 （共 6 条）
反应条件
ethanol; sodium 2 h; Reflux;
参考文献
Vigo, Daniele; Stasi, Luigi; Gagliardi, Stefania
Tetrahedron Letters, 2011 , vol. 52, # 5 p. 565 - 567
反应条件
in water T=70°C; pH=7.06; Kinetics; Further Variations:TemperaturespH-values;
参考文献
Environmental Science and Technology, , vol. 39, # 2 p. 505 - 512
参考文献
TIBOTEC PHARMACEUTICALS LTD.
Patent: WO2008/99020 A1, 2008 ;
Location in patent: Page/Page column 157-158 ;
参考文献
Lonza Ltd.
Patent: US5486622 A1, 1996 ;
反应条件
thionyl chloride in dichloromethane
参考文献
SCHERING CORPORATION
Patent: WO2009/61699 A1, 2009 ;
Location in patent: Page/Page column 348-349 ;
WO 2009/061699 A1
反应条件
hydrogen iodide
Heating;
参考文献
Borremans,F.; Anteunis,M.J.O.
Bulletin des Societes Chimiques Belges, 1976 , vol. 85, p. 681 - 696
