4,5-二氨基-2-氟苯甲腈合成路线 （共 4 条）
反应条件
1: NH3 2: H2 / Pd/C / 760 Torr View Scheme
参考文献
ADAMS, Christopher Michael; BABU, Charles; CAPPARELLI, Michael Paul; DING, Jian; EHARA, Takeru; JENDZA, Keith; JI, Nan; KARKI, Rajeshri Ganesh; KAWANAMI, Toshio; LIANG, Xue; MAINOLFI, Nello; POWERS, James J.; SERRANO-WU, Michael H.; ZHANG, Chun
Patent: US2013/296377 A1, 2013 ;
Location in patent: Paragraph 1122 ;
反应条件
hydrogen; palladium on activated charcoal P=760 Torr;
参考文献
Axys Pharmaceuticals, Inc.
Patent: US6150379 A1, 2000 ;
反应条件
sulfuric acid; potassium nitrate
参考文献
Axys Pharmaceuticals, Inc.
Patent: US6150379 A1, 2000 ;
反应条件
1: KNO3; 18 N H2SO4 2: NH3 3: H2 / Pd/C / 760 Torr View Scheme
参考文献
Mackman, Richard L.; Hui, Hon C.; Breitenbucher; Katz, Bradley A.; Luong, Christine; Martelli, Arnold; McGee, Danny; Radika, Kesavan; Sendzik, Martin; Spencer, Jeffrey R.; Sprengeler, Paul A.; Tario, James; Verner, Erik; Wang, Jing
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 15 p. 2019 - 2022
