1: 72 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / Ambient temperature 2: 17 percent / aq. NH4OH / methanol; tetrahydrofuran / 168 h / Ambient temperature 3: 72 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature 4: 77 percent / pyridine / 3.5 h / Ambient temperature 5: 45 percent / 1 N aq. HCl / aq. ethanol / 4 h / Ambient temperature View Scheme

1: 72 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / Ambient temperature 2: 17 percent / aq. NH4OH / methanol; tetrahydrofuran / 168 h / Ambient temperature 3: 72 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature 4: 0.1 M aq. KMnO4 / acetone / 1 h / Ambient temperature 5: 1 N aq. HCl / ethanol / 18 h / Ambient temperature View Scheme

1: 39 percent / SeO2 / dioxane; H2O / 24 h / Heating 2: 97 percent / pyridinium tosylate / CH2Cl2 / 24 h / Ambient temperature 3: 99 percent / 10percent aq. NaOH / methanol / 0.67 h / Ambient temperature View Scheme

1: 39 percent / SeO2 / dioxane; H2O / 24 h / Heating 2: 97 percent / pyridinium tosylate / CH2Cl2 / 24 h / Ambient temperature 3: 99 percent / 10percent aq. NaOH / methanol / 0.67 h / Ambient temperature 4: 98 percent / triethylamine / CH2Cl2 / 17 h / 0 °C 5: 88 percent / triethylamine / CH2Cl2 / 12 h / Ambient temperature 6: 54 percent / pyridinium tosylate / aq. ethanol / 24 h / 50 °C View Scheme

1: 39 percent / SeO2 / dioxane; H2O / 24 h / Heating 2: 97 percent / pyridinium tosylate / CH2Cl2 / 24 h / Ambient temperature 3: 99 percent / 10percent aq. NaOH / methanol / 0.67 h / Ambient temperature 4: 76 percent / triethylamine / CH2Cl2 / 24 h / Ambient temperature 5: 76 percent / pyridinium tosylate / aq. ethanol / 24 h / 50 °C View Scheme

1: 72 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / Ambient temperature 2: 17 percent / aq. NH4OH / methanol; tetrahydrofuran / 168 h / Ambient temperature 3: 1.) pyridine, 2.) 2 N aq. HCl / 1.) CH2Cl2, RT, 16 h, 2.) aq. EtOH, RT, 22 h View Scheme

1: 39 percent / SeO2 / dioxane; H2O / 24 h / Heating 2: 97 percent / pyridinium tosylate / CH2Cl2 / 24 h / Ambient temperature 3: 99 percent / 10percent aq. NaOH / methanol / 0.67 h / Ambient temperature 4: 98 percent / triethylamine / CH2Cl2 / 17 h / 0 °C 5: 88 percent / triethylamine / CH2Cl2 / 12 h / Ambient temperature 6: 54 percent / pyridinium tosylate / aq. ethanol / 24 h / 50 °C 7: 78 percent / Me2SO, trifluoroacetic anhydride / CH2Cl2 / 0.5 h / -78 °C View Scheme

1: 39 percent / SeO2 / dioxane; H2O / 24 h / Heating 2: 97 percent / pyridinium tosylate / CH2Cl2 / 24 h / Ambient temperature 3: 99 percent / 10percent aq. NaOH / methanol / 0.67 h / Ambient temperature 4: 76 percent / triethylamine / CH2Cl2 / 24 h / Ambient temperature 5: 76 percent / pyridinium tosylate / aq. ethanol / 24 h / 50 °C 6: 77 percent / Me2SO, trifluoroacetic anhydride / CH2Cl2 / 0.5 h / -78 °C View Scheme