4-氨基-5-苯基-4H-1,2,4-三唑-3-硫醇合成路线 （共 34 条）
反应条件
1: 85 percent / dimethylformamide / 10 h / Ambient temperature 2: dimethylformamide / 24 h / Heating View Scheme
参考文献
Chaturvedi, Bandana; Tiwari, Nirupama; Nizamuddin
Agricultural and Biological Chemistry, 1988 , vol. 52, # 5 p. 1229 - 1232
反应条件
1: With potassium hydroxide in water
2: With hydrogenchloride in water
4 h; Reflux;
参考文献
Xia, Qingchun; Xu, Dongfang; He, Qizhuang; Li, Xingyu; Sun, Dazhi
Chinese Journal of Chemistry, 2010 , vol. 28, # 12 p. 2433 - 2440
反应条件
sodium salt of the chloroacetic acid; sodium carbonate
参考文献
Sung; Lee
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1101 - 1109
反应条件
1: 33 percent / K2CO3 / dimethylformamide / 48 h / 20 °C
2: 54 percent / 0.5 h / 750 °C / 0.01 Torr
View Scheme
参考文献
Cartwright, Dale D.J.; Clark, Bernard A.J.; McNab, Hamish
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 4 p. 424 - 428
反应条件
trichlorophosphate
Heating;
参考文献
Chadha, Vijay K.; Sharma, G. R.
Journal of the Indian Chemical Society, 1980 , vol. 57, p. 1112 - 1114
反应条件
in ethanol
Alkylation; cyclization; 1 h; Heating;
参考文献
El-Barbary, A. A.; Fahmy, M.; El-Badawi, M.; El-Brembaly, K.; El-Brollosi, N. R.
Revue Roumaine de Chimie, 1991 , vol. 36, # 4-7 p. 619 - 628
反应条件
sulfuric acid in acetic acid
3 h; Reflux;
参考文献
El-Sherief, Hassan A. H.; Hozien, Zeniab A.; El-Mahdy, Ahmed F. M.; Sarhan, Abdelwareth A. O.
Synthesis, 2010 , # 15 art. no. Z06710SS, p. 2636 - 2642
反应条件
tetrabutylammomium bromide; potassium carbonate in benzene
a) RT, 2 h, b) 60 deg C, 3 h;
参考文献
Sultan, Adel A.
Phosphorus, Sulfur and Silicon and the Related Elements, 1995 , vol. 105, # 1-4 p. 123 - 128
反应条件
in ethanol
5 h; Heating;
参考文献
Eweiss, N. F.; Bahajaj, A. A.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1173 - 1182
反应条件
1: 72 percent / K2CO3 / ethanol / 3 h / Heating
2: 60 percent / POCl3 / 0.25 h / Heating
View Scheme
参考文献
El-Barbary, A. A.; Fahmy, M.; El-Badawi, M.; El-Brembaly, K.; El-Brollosi, N. R.
Revue Roumaine de Chimie, 1991 , vol. 36, # 4-7 p. 619 - 628
