2,2,2’,4’-四氯苯乙酮合成路线 （共 12 条）
反应条件
chloro-trimethyl-silane; potassium nitrate in dichloromethane T=60°C; 16 h;
参考文献
Prakash, G.K. Sxurya; Ismail, Rehana; Garcia, Jessica; Panja, Chiradeep; Rasul, Golam; Mathew, Thomas; Olah, George A.
Tetrahedron Letters, 2011 , vol. 52, # 11 p. 1217 - 1221
反应条件
BnNMe3(1+)ICl4(1-); acetic acid T=70°C; 6 h;
参考文献
Kakinami, Takaaki; Urabe, Yasuaki; Hermawan, Irwan; Yamanishi, Hiroko; Okamoto, Tsuyoshi; Kajigaeshi, Shoji
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 9 p. 2549 - 2551
反应条件
aluminium trichloride 1.) 60-65 deg C, 4 h; 2.) reflux, 110-115 deg C, 8 h; 3.) 25 deg C, 24 h;
参考文献
Mahato, Shashi B.; Mandal, Nirup B.; Pal, Anil K.; Maitra, Swapan K.
Tetrahedron, 1987 , vol. 43, # 19 p. 4439 - 4446
反应条件
1: 1.) Zn(Cu) couple, 2.) Pd(PPh3)4 / 1.) DMF, benzene, room temp., 1 h, then 60 deg C, 4 h, 2.) DMF, benzene, room temp., 1 h 2: 80 percent / benzyltrimethylammonium tetrachloroiodate / acetic acid / 2.5 h / 70 °C View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 41, # 4 p. 261 - 266
反应条件
2: TsOH / 165 °C View Scheme
参考文献
Pilgram,K. et al.
Journal of Organic Chemistry, 1969 , vol. 34, p. 3558 - 3561
反应条件
in diethyl ether 1.5 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fudala, Louise; Lewin, Anita H.
Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 4 p. 261 - 266
反应条件
in methanol 0.25 h; Heating; Title compound not separated from byproducts;
参考文献
Mlotkowska, Barbara; Majewski, Piotr; Koziara, Anna; Zwierzak, Andrzej; Sledzinski, Bohdan
Polish Journal of Chemistry, 1981 , vol. 55, # 3 p. 631 - 642
反应条件
in diethyl ether 1.5 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fudala, Louise; Lewin, Anita H.
Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 4 p. 261 - 266
反应条件
in methanol 0.25 h; Heating; Title compound not separated from byproducts;
参考文献
Mlotkowska, Barbara; Majewski, Piotr; Koziara, Anna; Zwierzak, Andrzej; Sledzinski, Bohdan
Polish Journal of Chemistry, 1981 , vol. 55, # 3 p. 631 - 642
反应条件
in diethyl ether 1.5 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fudala, Louise; Lewin, Anita H.
Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 4 p. 261 - 266
