1: 3-(bromo)propionic acid ethyl ester With pyrene; zinc in N,N-dimethyl-formamide
T=20°C; 1 h;
2: para-iodoanisole With bis (triortho-tolylphosphine)palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=70°C; 3 h;
1: With tri-tert-butyl phosphine; caesium carbonate; bis(1,5-cyclooctadiene)nickel (0) in hexane; toluene
T=0 - 20°C;
2: With hydrogenchloride in hexane; toluene
Further stages.;
1: 3-(4-methoxyphenyl)-propionic acid With 1H-imidazole; iodine; tris-(o-tolyl)phosphine in dichloromethane
T=20°C; Garegg-Samuelsson type reaction; 0.0833333 h;
2: ethanol With isopropyl alcohol in dichloromethane
T=20°C; Garegg-Samuelsson type reaction; chemoselective reaction;
参考文献
Morcillo, Sara P.; Alvarez De Cienfuegos, Luis; Mota, Antonio J.; Justicia, Jose; Robles, Rafael
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2277 - 2281
