1: 10percent KOH / methanol; H2O / 2 h / Heating 2: thionyl chloride / 1.5 h / Heating 3: K2CO3 / benzene; diethyl ether / Ambient temperature 4: lithium aluminum hydride (LAH) 5: 15 percent / acetonitrile / Irradiation View Scheme

1: 95 percent / sodium methoxide / methanol / 72 h 2: 95 percent / lithium aluminum hydride (LAH) 3: 57 percent Chromat. / acetonitrile / Irradiation View Scheme

1: 100 percent / DIBALH / tetrahydrofuran; CH2Cl2 / 4 h / -78 °C 2: 89 percent / I2; PPh3; imidazole / CH2Cl2 / 0 - 20 °C 3: 47 percent / cesium carbonate / acetonitrile / 72 h / 20 °C View Scheme

1: 100 percent / DIBALH / tetrahydrofuran; CH2Cl2 / 4 h / -78 °C 2: 89 percent / I2; PPh3; imidazole / CH2Cl2 / 0 - 20 °C 3: 47 percent / cesium carbonate / acetonitrile / 72 h / 20 °C 4: 74 percent / H2O / tetrahydrofuran / 4 h / 165 °C / microwave irradiation View Scheme

1: 100 percent / DIBALH / tetrahydrofuran; CH2Cl2 / 4 h / -78 °C 2: 87 percent / DMSO; oxalyl chloride; triethylamine / CH2Cl2 / 5.25 h / -78 - 20 °C 3: 49 percent / BH3*HNMe2 / methanol / 3 h / 20 °C View Scheme

1: 100 percent / DIBALH / tetrahydrofuran; CH2Cl2 / 4 h / -78 °C 2: 87 percent / DMSO; oxalyl chloride; triethylamine / CH2Cl2 / 5.25 h / -78 - 20 °C 3: 49 percent / BH3*HNMe2 / methanol / 3 h / 20 °C 4: 77 percent / cesium carbonate / acetonitrile / 72 h / 20 °C 5: 61 percent / H2O / tetrahydrofuran / 4 h / 165 °C / microwave irradiation View Scheme

1: 95 percent / sodium methoxide / methanol / 72 h 2: 95 percent / lithium aluminum hydride (LAH) 3: acetonitrile / Irradiation View Scheme