3,5-二氯-2-甲氧基苯甲酸合成路线 （共 13 条）
反应条件
potassium hydroxide in methanol Hydrolysis; Heating;
参考文献
Banks, William R.; Moerlein, Stephen M.; Parkinson, David; Welch, Michael J.
Medicinal Chemistry Research, 1995 , vol. 5, # 2/3 p. 150 - 173
反应条件
potassium carbonate in acetone 24 h; Reflux;
参考文献
Steffen, Jamin D.; Coyle, Donna L.; Damodaran, Komath; Beroza, Paul; Jacobson, Myron K.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5403 - 5413
反应条件
sodium hydroxide in water T=95 - 100°C; 4 h;
参考文献
Russian Journal of General Chemistry, , vol. 74, # 5 p. 738 - 743
反应条件
1: 95 percent / chlorine / acetic acid / 35 °C 2: sodium hydroxide / H2O / 4 h / 95 - 100 °C View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 74, # 5 p. 738 - 743
参考文献
Gazzetta Chimica Italiana, , vol. 29 II, p. 60
反应条件
chlorine; acetic acid
参考文献
Proceedings - Indian Academy of Sciences, Section A, , vol. <A> 8, p. 208,212, 213
反应条件
1: potassium hydroxide; methanol 2: HNO3 View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 29 II, p. 60
反应条件
1: sulfuryl chloride 2: potassium hydroxide; methanol 3: HNO3 View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 29 II, p. 60
参考文献
Gazzetta Chimica Italiana, , vol. 29 II, p. 60
反应条件
1: (COCl)2, DMF / tetrahydrofuran
2: pyridine
3: 68 percent / n-butyllithium / tetrahydrofuran; diethyl ether; hexane / 2 h / -70 °C
4: 95 percent / KOH / methanol / Heating
View Scheme
参考文献
Horne, Stephen; Rodrigo, Russell
Journal of Organic Chemistry, 1990 , vol. 55, # 15 p. 4520 - 4522
