(R)-2-氨基-3-羟基-3-甲基丁酸合成路线 （共 18 条）
反应条件
1: 40percent HBr / 3 h / Heating 2: methyloxirane / ethanol / 0.25 h / Heating View Scheme
参考文献
Synthesis, , # 10 p. 868 - 870
反应条件
1: 1.) 0.1 N aq. HCl, 2.) 25percent aq. NH3 / 1.) room temp., 12 h 2: 40percent HBr / 3 h / Heating 3: methyloxirane / ethanol / 0.25 h / Heating View Scheme
参考文献
Synthesis, , # 10 p. 868 - 870
反应条件
1: H2 / Pd-C 2: aq. NaOH 3: aq. HCl / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 39, p. 2287 - 2289
反应条件
1: 0.25 N HCl / H2O / 0.5 h / Ambient temperature 2: 64 percent / 3N HCl / 1 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 7 p. 1133 - 1151
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Nature Chemistry, , vol. 2, # 4 p. 280 - 285
反应条件
hydrogenchloride Heating;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 39, p. 2287 - 2289
反应条件
1: aq. NaOH 2: aq. HCl / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 39, p. 2287 - 2289
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water
参考文献
Inoue, Masayuki; Shinohara, Naoki; Tanabe, Shintaro; Takahashi, Tomoaki; Okura, Ken; Itoh, Hiroaki; Mizoguchi, Yuki; Iida, Maiko; Lee, Nayoung; Matsuoka, Shigeru
Nature Chemistry, 2010 , vol. 2, # 4 p. 280 - 285
