2-甲基-5-(4-硝基苯基)-1,3,4-噁二唑合成路线 （共 15 条）
反应条件
1: hydrazine hydrate / methanol / 0.5 h / |Reflux; |Inert atmosphere
2: N,N-dimethyl acetamide / 6 h / 0 °C / |Inert atmosphere
3: trichlorophosphate / 20 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Conole, Daniel; Beck, Thorsten M.; Jay-Smith, Morgan; Tingle, Malcolm D.; Eason, Charles T.; Brimble, Margaret A.; Rennison, David
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2220 - 2235
反应条件
1: hexamethylphosphoric acid triamide / 1 h / 20 °C
2: hexamethylphosphoric acid triamide / 0.01 h / microwave irradiation
View Scheme
参考文献
Mashraqui, Sabir H.; Ghadigaonkar, Shailesh G.; Kenny, Rajesh S.
Synthetic Communications, 2003 , vol. 33, # 14 p. 2541 - 2545
参考文献
Golfier,M.; Guillerez,M.-G.
Tetrahedron Letters, 1976 , p. 267 - 270
参考文献
Huisgen,R. et al.
Chemische Berichte, 1960 , vol. 93, p. 2106 - 2124
参考文献
Vakula,T.R. et al.
Indian Journal of Chemistry, 1968 , vol. 6, p. 172 - 173
