D(-)-对羟基苯甘氨酸合成路线 （共 36 条）
反应条件
thionyl chloride in methanol T=20°C; 10 h;
参考文献
Mohammat, Mohd Fazli; Najim, Nigar; Mansor, Nurul Shulehaf; Sarman, Sharil; Shaameri, Zurina; Zain, Mazatulikhma Mat; Hamzah, Ahmad Sazali
Arkivoc, 2011 , vol. 2011, # 9 p. 429 - 438
反应条件
thionyl chloride T=-15°C; Inert atmosphereReflux;
参考文献
Slattery, Catherine N.; O'Keeffe, Sarah; Maguire, Anita R.
Tetrahedron Asymmetry, 2013 , vol. 24, # 20 p. 1265 - 1275
反应条件
thionyl chloride in methanol T=20°C; 10 h;
参考文献
Mohammat, Mohd Fazli; Najim, Nigar; Mansor, Nurul Shulehaf; Sarman, Sharil; Shaameri, Zurina; Zain, Mazatulikhma Mat; Hamzah, Ahmad Sazali
Arkivoc, 2011 , vol. 2011, # 9 p. 429 - 438
反应条件
1: 100 percent / SOCl2 / 10 h / 20 °C 2: 44 percent / aq. glyoxylic acid; copper(II) sulfate; pyridine / 10 h / 20 °C 3: 82 percent / aq. NaOH / 2 h / 20 °C View Scheme
参考文献
Chen, Yen Ting; Seto, Christopher T.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 3946 - 3952
反应条件
1: H2 / Ni-Raney 2: Et3N / dioxane; H2O / 36 h / Ambient temperature View Scheme
参考文献
Banfi, Aldo; Benedini, Francesca; Sala, Alberto; Russo, Giovanni
Synthetic Communications, 1990 , vol. 20, # 22 p. 3585 - 3597
反应条件
sodium carbonate in 1,4-dioxane T=0 - 20°C; 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 1 p. 56 - 70
