1: 1.) Pd(PPh3)4, aq. NaCO3; 2.) Mo(CO)6 / 1.) PhH, reflux; 2.) PhH, MeCN, H2O, reflux, 10 h 2: 80 percent / NaBH4, CeCl3 / methanol / 0 °C 3: 65 percent / Bu3P, DEAD / tetrahydrofuran / Ambient temperature 4: Dowex 50X8-100 / methanol / Ambient temperature 5: pyridine, DMAP / Ambient temperature 6: 40 percent / Tf2O, DMAP / CH2Cl2 / 0 °C 7: Amberlyst A21 / methanol / Ambient temperature 8: LiCl / dimethylformamide / 120 °C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: p-toluenesulfonic acid<br />2: 1.3 g / NaIO₄ / methanol; various solvent(s) / 16 h / 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: Escherichia coli JM₁₀₉ (pDTG₆₀₁A)<br />2: p-toluenesulfonic acid<br />3: 1.3 g / NaIO₄ / methanol; various solvent(s) / 16 h / 20 &deg;C<br /> <br /> &nbsp;