双环[2.2.1]庚烷-1-羧酸甲酯合成路线 （共 9 条）
反应条件
1: 25percent aq. NaOH 2: LiAlH4 / diethyl ether / 2.5 h / Heating 3: fuming sulfuric acid, 96percent aq. H2SO4 / 2 h / 20 °C 4: LiAlH4 / diethyl ether / 2 h / Heating 5: pyridinium fluorochromate / CH2Cl2 / Ambient temperature View Scheme
参考文献
Gudipati, Murthy S.; Radziszewski, Juliusz G.; Kaszynski, Piotr; Michl, Josef
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3668 - 3674
反应条件
sodium hydroxide Yield given;
参考文献
Adcock, William; Clark, Christopher I.
Journal of Organic Chemistry, 1995 , vol. 60, # 3 p. 723 - 724
参考文献
Kwart; Null
Journal of the American Chemical Society, 1959 , vol. 81, p. 2765,2770
Full Text Show Details
Fossey, Jacques; Lefort, Daniel
Tetrahedron, 1980 , vol. 36, # 81 p. 1023 - 1036
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in diethyl ether
T=0°C; 4 h; Irradiation;
参考文献
Adcock, William; Clark, Christopher I.
Journal of Organic Chemistry, 1995 , vol. 60, # 3 p. 723 - 724
反应条件
sodium tetrahydroborate; trimethylstannyl chloride
1) EtOH, below 15 deg C, irradiation, 3 h, 2) MeCOMe, 15 min; Multistep reaction;
参考文献
Gudipati, Murthy S.; Radziszewski, Juliusz G.; Kaszynski, Piotr; Michl, Josef
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3668 - 3674
反应条件
1: 1 h / Heating
2: 1) NaBH4, Sn(CH3)3Cl / 1) EtOH, below 15 deg C, irradiation, 3 h, 2) MeCOMe, 15 min
View Scheme
参考文献
Gudipati, Murthy S.; Radziszewski, Juliusz G.; Kaszynski, Piotr; Michl, Josef
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3668 - 3674
反应条件
1: SOCl2 / 2 h / Heating
2: 1 h / Heating
3: 1) NaBH4, Sn(CH3)3Cl / 1) EtOH, below 15 deg C, irradiation, 3 h, 2) MeCOMe, 15 min
View Scheme
参考文献
Gudipati, Murthy S.; Radziszewski, Juliusz G.; Kaszynski, Piotr; Michl, Josef
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3668 - 3674
反应条件
1: 96 percent Chromat. / benzene / 81 °C
View Scheme
参考文献
Fossey, Jacques; Lefort, Daniel
Tetrahedron, 1980 , vol. 36, # 81 p. 1023 - 1036
反应条件
1: reduction
View Scheme
参考文献
Fossey, Jacques; Lefort, Daniel
Tetrahedron, 1980 , vol. 36, # 81 p. 1023 - 1036
