5-甲基-1,3-苯并噁唑-2(3H)-酮合成路线 （共 20 条）
反应条件
1: ethanol; Raney nickel / 75 °C / 51485.6 Torr / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 71, p. 1265,1266
反应条件
sodium hydroxide in methanol; water Yield given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 28, # 8 p. 1937 - 1939
反应条件
hydrogenchloride T=20°C; 2 h;
参考文献
Medicinal Chemistry Research, , vol. 9, # 7-8 p. 631 - 642
反应条件
in acetone 4 h; Heating;
参考文献
Synthetic Communications, , vol. 20, # 5 p. 693 - 701
反应条件
carbon monoxide; triethylamine in 1,2-dichloro-benzene T=200°C; P=53200 Torr; 5 h; other tertiary amines, var. solvent, var. time; Product distribution;
参考文献
Gazzetta Chimica Italiana, , vol. 123, # 12 p. 683 - 686
反应条件
in acetone 4 h; Heating;
参考文献
Synthetic Communications, , vol. 20, # 5 p. 693 - 701
参考文献
Roczniki Chemii, , vol. 28, p. 549,554, 555
Chem.Abstr., , p. 305
参考文献
DE184689 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 8, p. 614
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=50°C; 2 h;
参考文献
ALANTOS PHARMACEUTICALS, INC.
Patent: US2007/155739 A1, 2007 ;
Location in patent: Page/Page column 33 ;
US 20070155739 A1
反应条件
sodium hydroxide
T=0°C; Methylation; 3.5 h;
参考文献
Liacha, Messaoud; Yous, Said; Depreux, Patrick; Poupaert, Jacques H.; Lesieur, Daniel
Heterocycles, 1999 , vol. 51, # 8 p. 1929 - 1943
