N-乙酰基神经氨酸甲基酯合成路线 (共 10 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
KANDULA, mahesh
Patent: WO2013/14565 A1, 2013 ;
Location in patent: Paragraph 00190-00192 ;
反应条件
1: With hydrogenchloride in water T=20°C; 6 h; 2: With triethylamine in water Product distribution / selectivity;
参考文献
GLYCOM A/S; PEREZ FIGUEROA, Ignacio; HORVATH, Ferenc; DEKANY, Gyula; RISINGER, Christian; HEDEROS, Markus
Patent: WO2012/113404 A1, 2012 ;
Location in patent: Page/Page column 14 ;
参考文献
GelTex Pharmaceuticals, Inc.
Patent: US5891862 A1, 1999 ;
反应条件
Dowex 50WX4 (H+) T=20°C;
参考文献
Sardzik, Robert; Noble, Gavin T.; Weissenborn, Martin J.; Martin, Andrew; Webb, Simon J.; Flitsch, Sabine L.
Beilstein Journal of Organic Chemistry, 2010 , vol. 6, p. 699 - 703
反应条件
palladium 10 on activated carbon; cyclohexene in methanol 16 h; Reflux;
参考文献
Bressel, Bettina; Reissig, Hans-Ulrich
Organic Letters, 2009 , vol. 11, # 3 p. 527 - 530
反应条件
acetic acid in methanol; water 0.5 h; Ambient temperature;
参考文献
Sato; Furuhata; Ogura
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 12 p. 4678 - 4688
参考文献
Allevi, Pietro; Rota, Paola; Scaringi, Raffaella; Colombo, Raffaele; Anastasia, Mario
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5542 - 5548
反应条件
trifluoroacetic acid T=0 - 20°C; 48 h; optical yield given as percent de;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 5 p. 931 - 934
反应条件
trifluoroacetic acid T=140°C; 0.0833333 h; Microwave irradiation; TemperatureTime;
参考文献
New Journal of Chemistry, , vol. 38, # 2 p. 507 - 510
反应条件
1: T=20°C; 12 h; 2: With methanol; ozone T=-78°C; 0.166667 h;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 50 p. 12054 - 12057