苯并[b]噻吩-2-羧酸甲酯合成路线 （共 28 条）
反应条件
1,4-diaza-bicyclo[2.2.2]octane; triethanolamine; acrylic acid methyl ester T=20°C; 144 h;
参考文献
Ahn, Sang-Hyun; Jang, Seung Soon; Kim, Young Keun; Lee, Kee-Jung
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 1 p. 233 - 242
反应条件
in dichloromethane T=20°C; Wittig reaction; 2 h;
参考文献
Tetrahedron Letters, , vol. 46, # 21 p. 3719 - 3723
反应条件
in dimethyl sulfoxide
反应条件
chloro-trimethyl-silane
参考文献
Tietze, Lutz F.; Lohmann, J. Klaas; Stadler, Christian
Synlett, 2004 , # 6 p. 1113 - 1116
反应条件
1: hydrofluoroboric acid; sodium nitrite / water / 0.67 h / 0 - 5 °C 2: Eosin / dimethyl sulfoxide / 14 h / 20 °C / |Irradiation View Scheme
参考文献
Organic Letters, , vol. 14, # 20 p. 5334 - 5337,4
反应条件
1.1: potassium hydroxide / water / 17 h / |Reflux 1.2: 1 h / 20 °C 2.1: hydrofluoroboric acid; sodium nitrite / water / 0.67 h / 0 - 5 °C 3.1: Eosin / dimethyl sulfoxide / 14 h / 20 °C / |Irradiation View Scheme
参考文献
Organic Letters, , vol. 14, # 20 p. 5334 - 5337,4
反应条件
1.1: acetic acid; bromine / 3 h / 10 °C 2.1: potassium hydroxide / water / 17 h / |Reflux 2.2: 1 h / 20 °C 3.1: hydrofluoroboric acid; sodium nitrite / water / 0.67 h / 0 - 5 °C 4.1: Eosin / dimethyl sulfoxide / 14 h / 20 °C / |Irradiation View Scheme
参考文献
Organic Letters, , vol. 14, # 20 p. 5334 - 5337,4
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: tetrahydrofuran 2.1: K2CO3 / dimethylformamide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 12 p. 2998 - 3001
反应条件
1: 59 percent / PCC / CH2Cl2 / 4 h / 20 °C 2: 20 percent / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 21 p. 3719 - 3723
反应条件
1: 96 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h 2: 59 percent / PCC / CH2Cl2 / 4 h / 20 °C 3: 20 percent / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 21 p. 3719 - 3723
