2-溴-5-甲氧基苯甲酸合成路线 （共 95 条）
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 88, p. 340
参考文献
Justus Liebigs Annalen der Chemie, , vol. 391, p. 44
参考文献
Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, , vol. 3/, p. 153
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 88, p. 340
反应条件
thionyl chloride T=40°C; Esterification; 18 h;
参考文献
Ozaki, Shigeko; Adachi, Masashi; Sekiya, Sayaka; Kamikawa, Rie
Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4586 - 4589
参考文献
Amgen Inc.
Patent: US6514964 B1, 2003 ;
反应条件
copper quinolate in water; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Zhu, Yan; Yan, Hong; Lu, Linhua; Liu, Defu; Rong, Guangwei; Mao, Jincheng
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9898 - 9905
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile Reflux;
参考文献
Shen, Zhongqi; Siva Ramamoorthy; Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Childers, Wayne; Harrison, Boyd L.; Chlenov, Michael; Hornby, Geoffrey; Smith, Deborah L.; Sullivan, Kelly M.; Schechter, Lee E.; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 222 - 227
反应条件
copper(I) bromide in pyridine 3 h; Heating / reflux;
参考文献
ROCHE DIAGNOSTICS GMBH; F. HOFFMANN-LA ROCHE AG
Patent: WO2008/52742 A1, 2008 ;
Location in patent: Page/Page column 22; Sheet 4 ;
反应条件
n-butyllithium 1) 1 h, -100 deg C, 2) THF, 1 h, -78 deg C; Yield given. Multistep reaction;
参考文献
SANOFI-AVENTIS
Patent: US2007/99895 A1, 2007 ;
Location in patent: Page/Page column 9 ;
