4,6-二甲基-3-硝基吡啶-2-胺合成路线 （共 13 条）
反应条件
hydrogen; palladium on activated charcoal in various solvent(s)
参考文献
Stucky, Gerhard C.; Roduit, Jean-Paul; Schmidt, Beat
Chimia, 1997 , vol. 51, # 6 p. 280 - 282
反应条件
H2; palladium monocarbide in methanol
参考文献
Merck and Co., Inc.
Patent: US5049565 A1, 1991 ;
US 5049565 A
反应条件
H2; palladium monocarbide in methanol
参考文献
Merck and Co., Inc.
Patent: US5177074 A1, 1993 ;
反应条件
1: H2 / 10percent Pd/C / methanol / 760 Torr 2: polyphosphoric acid / 80 - 90 °C View Scheme
参考文献
Mantlo, Nathan B.; Chakravarty, Prasun K.; Ondeyka, Debra L.; Siegl, Peter K. S.; Chang, Raymond S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2919 - 2922
反应条件
sulfuric acid; hydrogen; palladium on activated charcoal
参考文献
Stucky, Gerhard C.; Roduit, Jean-Paul; Schmidt, Beat
Chimia, 1997 , vol. 51, # 6 p. 280 - 282
反应条件
1: H2 / 10percent Pd/C / methanol / 760 Torr 2: polyphosphoric acid / 80 - 90 °C View Scheme
参考文献
Mantlo, Nathan B.; Chakravarty, Prasun K.; Ondeyka, Debra L.; Siegl, Peter K. S.; Chang, Raymond S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2919 - 2922
参考文献
Merck and Co., Inc.
Patent: US5177074 A1, 1993 ;
反应条件
conc H2SO4 in ethyl acetate
参考文献
MERCK and CO. INC.
Patent: EP456510 A1, 1991 ;
EP 0456510 A1
Title/Abstract Full Text Show Details
MERCK and CO. INC.
Patent: EP467715 A1, 1992 ;
EP 0467715 A1
反应条件
in 2-methoxy-ethanol
参考文献
Stucky, Gerhard C.; Roduit, Jean-Paul; Schmidt, Beat
Chimia, 1997 , vol. 51, # 6 p. 280 - 282
反应条件
in ethanol
16 h; Heating;
参考文献
Batt; Houghton
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 963 - 969
