1-(3-乙基-4-羟基苯基)乙酮合成路线 （共 6 条）
反应条件
aluminium trichloride in carbon disulfide 1.) RT, 1 h, 2.) reflux, 12 h;
参考文献
Leclerc, Gerard; Bizec, Jean Claude; Bieth, Nicole; Schwartz, Jean
Journal of Medicinal Chemistry, 1980 , vol. 23, # 7 p. 738 - 744
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate in tetrahydrofuran Suzuki-Miyaura cross-coupling; Inert atmosphereReflux;
参考文献
Wang, Bing; Sun, Hui-Xia; Sun, Zhi-Hua; Lin, Guo-Qiang
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 3 p. 415 - 422
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate in tetrahydrofuran Suzuki coupling; Inert atmosphereReflux; chemoselective reaction;
参考文献
Sun, Hui-Xia; Sun, Zhi-Hua; Wang, Bing
Tetrahedron Letters, 2009 , vol. 50, # 14 p. 1596 - 1599
反应条件
aluminium trichloride in nitrobenzene
参考文献
Schroetter; Schubert
Die Pharmazie, 1970 , vol. 25, # 4 p. 242 - 245
反应条件
ueber das Acetyl-Derivat;
参考文献
McCoubrey
Journal of Pharmacy and Pharmacology, 1956 , vol. 8, p. 648,649
反应条件
1: aq. NaOH
2: Br2, aq. NaOH / methanol
3: aq. HBr, AcOH / Heating
4: H2SO4 / 1,2-dichloro-ethane / Heating
View Scheme
参考文献
Begue,J.-P.; Fetizon,M.
Bulletin de la Societe Chimique de France, 1969 , p. 781 - 787
