7-甲氧基-1,3-苯并二氧化物-5-甲醇合成路线 （共 16 条）
反应条件
1: 91 percent / PCC, NaOAc / CH2Cl2 / 2 h 2: 1) n-BuLi / 1) THF, -50 deg C to RT, 20 min, 2) THF, RT, 30 min View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 65, # 10 p. 2390 - 2396
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; Swern oxidation; 0.5 h; Inert atmosphere; 2: With triethylamine in dichloromethane T=-78 - 20°C; Swern oxidation; Inert atmosphere;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 4 p. 440 - 448
反应条件
in (7-methoxybenzo[3,4-d]1,3-dioxolan-5-yl)methan-1-ol(7.63 g, Yield 88); dichloromethane
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether
0.5 h;
参考文献
Pettit; Singh
Canadian Journal of Chemistry, 1987 , vol. 65, # 10 p. 2390 - 2396
反应条件
sodium tetrahydroborate in methanol; dichloromethane
参考文献
Lalami, Khalid; Dhal, Robert; Brown, Eric
Heterocycles, 1988 , vol. 27, # 5 p. 1131 - 1134
反应条件
in ether-tetrahydrofuran
参考文献
ARIZONA BOARD OF REGENTS
Patent: EP276051 B1, 1991 ;
反应条件
lithium aluminium tetrahydride in diethyl ether
T=0°C; 0.416667 h; Inert atmosphere;
参考文献
Altemoeller, Martina; Gehring, Timo; Cudaj, Judith; Podlech, Joachim; Goesmann, Helmut; Feldmann, Claus; Rothenberger, Alexander
European Journal of Organic Chemistry, 2009 , # 13 p. 2130 - 2140
反应条件
1: 10.4 g / K2CO2 / dimethylformamide / 4 h / Heating
2: 89.3 percent / NaBH4; I2 / tetrahydrofuran / 8 h / Heating
View Scheme
参考文献
Zhang, Wei-Ge; Zhao, Rui; Ren, Jian; Ren, Li-Xiang; Lin, Jin-Guang; Liu, Dai-Lin; Wu, Ying-Liang; Yao, Xin-Sheng
Archiv der Pharmazie, 2007 , vol. 340, # 5 p. 244 - 250
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
2 h; Ambient temperature;
参考文献
Asakawa, Yoshinori; Matsuda, Reiko; Cheminat, Annie
Phytochemistry (Elsevier), 1987 , vol. 26, # 4 p. 1117 - 1122
反应条件
1: 2.88 g / 5percent H3BO3, NaOH / Ambient temperature
2: 1.90 g / K2CO3, CuO / dimethylformamide / 3 h / 120 - 125 °C
3: 980 mg / LiAlH4 / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
参考文献
Asakawa, Yoshinori; Matsuda, Reiko; Cheminat, Annie
Phytochemistry (Elsevier), 1987 , vol. 26, # 4 p. 1117 - 1122
