1-苄基-1H-咪唑-2-胺合成路线 （共 2 条）
反应条件
hydrogen; nickel in methanol T=20°C; 3 h;
参考文献
NOVARTIS AG
Patent: WO2009/141386 A1, 2009 ;
Location in patent: Page/Page column 164 ;
WO 2009/141386 A1
反应条件
1: With acetic acid in water T=20 - 100°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in water T=100°C; 0.25 h; Inert atmosphere;
参考文献
Zhang, Liang; Sathunuru, Ramadas; Caridha, Diana; Pybus, Brandon; O'Neil, Michael T.; Kozar, Michael P.; Lin, Ai J.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6634 - 6646
