1,3-苯并二氧戊环-2-基甲醇合成路线 （共 2 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 1 h; 2: With sodium hydrogencarbonate in tetrahydrofuran; methanol; water T=0 - 20°C; 0.5 h;
参考文献
SHIONOGI and CO., LTD.; EURO-CELTIQUE S.A
Patent: WO2008/8398 A2, 2008 ;
Location in patent: Page/Page column 364-365 ;
反应条件
1: NaOMe / methanol / Heating 2: 0.75 g / LiAlH4 / tetrahydrofuran / 1 h View Scheme
参考文献
Torisu, Kazuhiko; Kobayashi, Kaoru; Iwahashi, Maki; Nakai, Yoshihiko; Onoda, Takahiro; Nagase, Toshihiko; Sugimoto, Isamu; Okada, Yutaka; Matsumoto, Ryoji; Nanbu, Fumio; Ohuchida, Shuichi; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 20 p. 5361 - 5378
