4-(萘-1-基)苯甲酸甲酯合成路线 （共 16 条）
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tripotassium phosphate monohydrate; 2-(2-methoxyphenyl)-1-methyl-3-(diphenylphosphino)-1H-indole in 1,4-dioxane
T=90°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere;
参考文献
So, Chau Ming; Chow, Wing Kin; Choy, Pui Ying; Lau, Chak Po; Kwong, Fuk Yee
Chemistry - A European Journal, 2010 , vol. 16, # 27 p. 7996 - 8001
反应条件
anhydrous dipotassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane
T=100 - 110°C; Suzuki-Miyaura coupling reaction; Inert atmosphere;
参考文献
Gao, Han; Li, You; Zhou, Yi-Guo; Han, Fu-She; Lin, Ying-Jie
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 309 - 314
反应条件
bis(triphenylphosphine)palladium(II) chloride; Diisobutylammonium hydride; tert.-butyl lithium; zinc(II) chloride in tetrahydrofuran
T=-78 - 20°C; 1 h;
参考文献
Summers; Mazdiyasni; Holms; Ratajczyk; Dyer; Carter
Journal of Medicinal Chemistry, 1987 , vol. 30, # 3 p. 574 - 580
反应条件
bis(1,5-cyclooctadiene)nickel (0); cesium fluoride; tri-cyclo-hexyl-phosphine in toluene
T=120°C; 19 h;
参考文献
Leowanawat, Pawaret; Zhang, Na; Percec, Virgil
Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 1018 - 1025
反应条件
potassium carbonate; PEG 6000 in water
0.0666667 h; Heatingmicrowave irradiation; other energy of irradiation, reaction time; Product distribution;
参考文献
Blettner, Carsten G.; Koenig, Wilfried A.; Stenzel, Wolfgang; Schotten, Theo
Journal of Organic Chemistry, 1999 , vol. 64, # 11 p. 3885 - 3890
反应条件
1.1: sodium hydride / ethylene glycol dimethyl ether / 0.17 h / 0 - 20 °C / Inert atmosphere
1.2: 12 h / 0 - 20 °C / Inert atmosphere
2.1: potassium phosphate; bis(1,5-cyclooctadiene)nickel (0); tri-cyclo-hexyl-phosphine / tetrahydrofuran / 12 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Leowanawat, Pawaret; Zhang, Na; Percec, Virgil
Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 1018 - 1025
