L-苯丙氨酰-L-异亮氨酸合成路线 (共 5 条)
反应条件
potassium hydroxide; potassium borate buffer in water T=3°C; pH 10.2;
参考文献
Kircher, K.; Berndt, H.; Zahn, H.
Liebigs Annalen der Chemie, 1980 , # 2 p. 275 - 284
反应条件
aminolysin-A in water; dimethyl sulfoxide T=50°C; pH=8; 6 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Usuki, Hirokazu; Yamamoto, Yukihiro; Arima, Jiro; Iwabuchi, Masaki; Miyoshi, Shozo; Nitoda, Teruhiko; Hatanaka, Tadashi
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2327 - 2335
反应条件
1: 100 percent / BOP, NMM / dimethylformamide / 2 h 2: 93 percent / TFA / 1 h / Ambient temperature View Scheme
参考文献
Doulut, Sylvie; Dubuc, Isabelle; Rodriguez, M.; Vecchini, F.; Fulcrand, H.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 10 p. 1369 - 1379
反应条件
1: 100 percent / BOP, NMM / dimethylformamide / 2 h 2: 93 percent / TFA / 1 h / Ambient temperature View Scheme
参考文献
Doulut, Sylvie; Dubuc, Isabelle; Rodriguez, M.; Vecchini, F.; Fulcrand, H.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 10 p. 1369 - 1379
反应条件
1: DCC, HOBt 2: H2 / Pd View Scheme
参考文献
Harada, Kaoru; Shiono, Katsuji; Nomoto, Shinya
Chemistry Letters, 1980 , p. 1271 - 1274