3-(2-甲氧基苯基)-丙酸氯合成路线 （共 16 条）
反应条件
1.1: 0.74 g / diethyl ether / 3 h / -20 - 20 °C 2.1: rhodium(II) acetate / CH2Cl2 / 1 h / Heating 2.2: 15 mg / TFA / CH2Cl2 / 0.17 h View Scheme
参考文献
Ghosh, Somnath; Datta, Indira; Chakraborty, Rupak; Das, Tapas Kumar; Sengupta, Judhajit; Sarkar, Dipak Chandra
Tetrahedron, 1989 , vol. 45, # 5 p. 1441 - 1446
反应条件
1: 98 percent / diethyl ether / Ambient temperature 2: 19 percent / <Rh(CH3COO)2>2, CF3COOH / CH2Cl2 / 0.42 h / Heating View Scheme
参考文献
McKervey, M. Anthony; Ratananukul, Piniti
Tetrahedron Letters, 1983 , vol. 24, # 1 p. 117 - 120
反应条件
aluminium trichloride
参考文献
Carpenter; Hunter
Journal of Applied Chemistry, 1951 , vol. 1, p. 217,223
Journal of the Chemical Society, 1954 , p. 2731,2735
反应条件
palladium; xylene Hydrogenation.Isolierung ueber das Natriumhydrogensulfit-Addukt;
参考文献
Zaki; Fahim
Journal of the Chemical Society, 1942 , p. 182
反应条件
in diethyl ether
Ambient temperature;
参考文献
Copinga, Swier; Tepper, Pieter G.; Grol, Cor J.; Horn, Alan S.; Dubocovich, Margarita L.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 20 p. 2891 - 2898
反应条件
1: 98 percent / diethyl ether / Ambient temperature
2: 19 percent / <Rh(CH3COO)2>2, CF3COOH / CH2Cl2 / 0.42 h / Heating
3: p-TsOH*H2O / benzene / 17 h / Heating
4: H2 / PtO2 / ethanol / 2.5 h / 1520 Torr
5: H2 / 10percent Pd/C / ethanol / 1 h / 45 °C / 2280 Torr
View Scheme
参考文献
Copinga, Swier; Tepper, Pieter G.; Grol, Cor J.; Horn, Alan S.; Dubocovich, Margarita L.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 20 p. 2891 - 2898
