1.1: sodium carbonate / hexane; water / 8 h / 20 °C 2.1: sodium hypochlorite / dichloromethane / 22 h / -10 - 20 °C 3.1: NiII chloride hexahydrate; sodium hydroxide; sodium tetrahydroborate / methanol / 2 h / -5 - 0 °C / |Inert atmosphere 3.2: 16 h / 20 °C 4.1: triethylamine / dichloromethane / 6 h / 20 °C 5.1: hydrogenchloride / diethyl ether / 14 h / 20 °C 6.1: sodium hydroxide / N,N-dimethyl-formamide / 2 h / 0 °C 6.2: 24.5 h / 0 - 20 °C 6.3: pH 8.3 - 8.5 View Scheme

sodium carbonate in n-heptane; water