1: 6N HCl / methanol / Ambient temperature 2: NaHCO3 / methanol / 0 °C 3: 1.) NaIO4, 2.) NaClO2, NaH2PO4 / 1.) acetone, H2O, RT, 2.) 2-methyl-2-butene, t-BuOH, H2O, RT 4: methanol / 0 °C 5: H2O, AcCl / methanol / Heating 6: NaHCO3 / H2O / Ambient temperature View Scheme

1: 6N HCl / methanol / Ambient temperature 2: NaHCO3 / methanol / 0 °C 3: 1.) NaIO4, 2.) NaClO2, NaH2PO4 / 1.) acetone, H2O, RT, 2.) 2-methyl-2-butene, t-BuOH, H2O, RT View Scheme