3,3',5,5'-四甲氧基-联苄基合成路线 （共 27 条）
反应条件
1: 75 percent / triethylamine / CCl4 / 1) 0 deg C, 1h, 2) RT, 16h 2: 67 percent / Li, liq. NH3 / tetrahydrofuran / 1 h View Scheme
参考文献
Saa, Jose M.; Dopico, Mercedes; Martorell, Gabriel; Garcia-Raso, Angel
Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 991 - 995
反应条件
1.1: PBr3 / CH2Cl2 / 0.75 h / -5 °C 2.1: 73 percent / 2.17 h / 140 - 180 °C 3.1: 61 percent / NaH; 15-crown-5 / tetrahydrofuran 4.1: Na / tetrahydrofuran / 18 h / 20 °C 4.2: 69 percent / H2O / tetrahydrofuran / 0 °C View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Idini, Maria Vittoria; Pisano, Luisa; Sechi, Grazia
Tetrahedron, 2003 , vol. 59, # 40 p. 7961 - 7966
反应条件
1.1: 73 percent / 2.17 h / 140 - 180 °C 2.1: 61 percent / NaH; 15-crown-5 / tetrahydrofuran 3.1: Na / tetrahydrofuran / 18 h / 20 °C 3.2: 69 percent / H2O / tetrahydrofuran / 0 °C View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Idini, Maria Vittoria; Pisano, Luisa; Sechi, Grazia
Tetrahedron, 2003 , vol. 59, # 40 p. 7961 - 7966
反应条件
1.1: 61 percent / NaH; 15-crown-5 / tetrahydrofuran 2.1: Na / tetrahydrofuran / 18 h / 20 °C 2.2: 69 percent / H2O / tetrahydrofuran / 0 °C View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Idini, Maria Vittoria; Pisano, Luisa; Sechi, Grazia
Tetrahedron, 2003 , vol. 59, # 40 p. 7961 - 7966
参考文献
Jaeger,D.A.
Journal of the American Chemical Society, 1974 , vol. 96, # 19 p. 6216 - 6217
反应条件
1: (i) LiAlH4, (ii) PBr3 2: Zn / tetrahydrofuran View Scheme
参考文献
Bullimore,B.K. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 1289 - 1293
参考文献
Pincock, J. A.; Wedge, P. J.
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5587 - 5595
反应条件
in methanol Irradiation;
参考文献
Pincock, J. A.; Wedge, P. J.
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5587 - 5595
反应条件
magnesium; chloromethyl-trimethyl-silane 1.) THF, 0 deg C, 0.5 h; to r.t. for 0.5 h; reflux, 1 h, 2.) THF, reflux, 6 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ali, Abdelselam S.; Liepa, Andris J.; Thomas, Mark D.; Wilkie, John S.; Winzenberg, Kevin N.
Australian Journal of Chemistry, 1994 , vol. 47, # 6 p. 1205 - 1210
反应条件
magnesium 1.) THF, 0 deg C, 0.5 h; to r.t. for 0.5 h; reflux, 1 h, 2.) THF, reflux, 6 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ali, Abdelselam S.; Liepa, Andris J.; Thomas, Mark D.; Wilkie, John S.; Winzenberg, Kevin N.
Australian Journal of Chemistry, 1994 , vol. 47, # 6 p. 1205 - 1210
