1-苯基-1,2,3,4-四氢异喹啉合成路线 （共 79 条）
反应条件
1: 92 percent / 10percent aq. NaOH / CH2Cl2 / 0.25 h 2: 1 g / POCl3, P2O5 / 2 h / Heating 3: H2 / PtO2 / ethanol / 10 h / 2792.6 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1242 - 1248
反应条件
hydrogenchloride in methanol 27 h; Heating;
参考文献
Seebach, Dieter; Lohmann, Jean-Jacques; Syfrig, Max A.; Yoshifuji, Masaaki
Tetrahedron, 1983 , vol. 39, # 12 p. 1963 - 1974
反应条件
sodium hydroxide in ethanol 20 h; Heating;
参考文献
Shinohara, Tatsumi; Takeda, Akira; Toda, Jun; Terasawa, Noriyo; Sano, Takehiro
Heterocycles, 1997 , vol. 46, # 1 p. 555 - 565
反应条件
trifluoroacetic acid in benzene 5 h; Heating;
参考文献
Kumar, P.; Dhawan, K. N.; Kishor, K.; Bhargaval, K. P.; Satsangi, R. K.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 677 - 679
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene T=80°C;
参考文献
Organic Letters, , vol. 3, # 7 p. 1009 - 1011
反应条件
1: molecular sieves 4 Angstroem / benzene / 25 °C 2: 67 percent / nBu3SnH; AIBN / benzene / 1 h / 85 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 1 p. 163 - 168
反应条件
1: 92 percent / 10percent aq. NaOH / CH2Cl2 / 0.25 h 2: 1 g / POCl3, P2O5 / 2 h / Heating 3: H2 / PtO2 / ethanol / 10 h / 2792.6 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1242 - 1248
反应条件
1: With hydrogenchloride; phosphoric acid; water T=95 - 100°C; 2: With sodium hydroxide in water T=20°C; pH=9 - 10; Product distribution / selectivity;
参考文献
WO2011/48607 A1, ;
Page/Page column 14 ;
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene 4 h; Heating;
参考文献
Tomaszewski, Miroslaw J.; Warkentin, John; Werstiuk, Nick H.
Australian Journal of Chemistry, 1995 , vol. 48, # 2 p. 291 - 322
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene Yields of byproduct given;
参考文献
Tomaszewski; Warkentin
Tetrahedron Letters, 1992 , vol. 33, # 16 p. 2123 - 2126
