1-苯基-1,2,3,4-四氢异喹啉合成路线 （共 79 条）
反应条件
1: toluene / 2 h / Heating 2: 75 percent / TFA / toluene / 5 h / Heating 3: NiCl2*6H2O, NaBH4 / methanol / Ambient temperature View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 2 p. 527 - 553
反应条件
1: 0.6 percent Chromat. / POCl3 / 0.5 h / Heating 2: toluene / 2 h / Heating 3: 75 percent / TFA / toluene / 5 h / Heating 4: NiCl2*6H2O, NaBH4 / methanol / Ambient temperature View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 2 p. 527 - 553
反应条件
1.1: sodium hydroxide / ethanol / 75 - 80 °C 1.2: Cooling 2.1: triethylamine / dichloromethane / -10 - 20 °C 3.1: hydrogenchloride; water; phosphoric acid / 32 h / 95 - 100 °C 3.2: 20 °C / pH 9 - 10 View Scheme
反应条件
sodium tetrahydroborate; iodine in tetrahydrofuran 16 h; Inert atmosphereReflux;
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
1: chlorine 2: aqueous ammonia 3: diethyl ether; benzene View Scheme
参考文献
Chemische Berichte, , vol. 91, p. 1133,1138
反应条件
1: aqueous ammonia 2: diethyl ether; benzene View Scheme
参考文献
Chemische Berichte, , vol. 91, p. 1133,1138
反应条件
1: methanol; ammonia 2: diethyl ether; benzene View Scheme
参考文献
Chemische Berichte, , vol. 91, p. 1133,1138
反应条件
diethyl ether; benzene
参考文献
Chemische Berichte, , vol. 91, p. 1133,1138
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 49, p. 130 - 133
参考文献
Heterocycles, , vol. 19, # 4 p. 653 - 656
