2,5-二乙基-1,3-噁唑-4-羧酸乙酯合成路线 （共 17 条）
反应条件
1.1: n-BuLi / tetrahydrofuran / -78 °C 1.2: tetrahydrofuran / 3 h / -78 °C 2.1: 97 percent / aq. KOH / ethanol / 0.08 h / 0 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 54, # 2 p. 196 - 203
反应条件
1.1: tetrahydrofuran / 12 h / Heating 2.1: n-BuLi / tetrahydrofuran / -78 °C 2.2: tetrahydrofuran / 3 h / -78 °C 3.1: 97 percent / aq. KOH / ethanol / 0.08 h / 0 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 54, # 2 p. 196 - 203
反应条件
lithium aluminium tetrahydride
参考文献
Ghosti, Arun K.; Kumaragurubaran, Nagaswamy; Hong, Lin; Lei, Hui; Hussain, Khaja Azhar; Liu, Chun-Feng; Devasamudram, Thippeswamy; Weerasena, Vajira; Turner, Robert; Koelsch, Gerald; Bilcer, Geoffrey; Tang, Jordan
Journal of the American Chemical Society, 2006 , vol. 128, # 16 p. 5310 - 5311
反应条件
diisobutylaluminium hydride in dichloromethane; toluene T=-78°C; 0.0833333 h;
参考文献
Ghosh, Arun K.; Kumaragurubaran, Nagaswamy; Hong, Lin; Kulkarni, Sarang S.; Xu, Xiaoming; Chang, Wanpin; Weerasena, Vajira; Turner, Robert; Koelsch, Gerald; Bilcer, Geoffrey; Tang, Jordan
Journal of Medicinal Chemistry, 2007 , vol. 50, # 10 p. 2399 - 2407
反应条件
1: KOH / H2O 2: SOCl2 View Scheme
参考文献
Ang, Kiah H.; Prager, Rolf H.; Smith, Jason A.; Weber, Ben; Williams, Craig M.
Tetrahedron Letters, 1996 , vol. 37, # 5 p. 675 - 678
反应条件
1: aqueous NaOH 2: CuO; quinoline View Scheme
参考文献
Cornforth; Cornforth
Journal of the Chemical Society, 1953 , p. 93,95
参考文献
Cornforth; Cornforth
Journal of the Chemical Society, 1953 , p. 93,95
