2-溴-3-羟基-6-甲基吡啶合成路线 （共 10 条）
反应条件
bromine in pyridine Ambient temperature;
参考文献
Mooring, Suazette Reid; Jin, Hui; Devi, Narra S.; Jabbar, Adnan A.; Kaluz, Stefan; Liu, Yuan; Van Meir, Erwin G.; Wang, Binghe
Journal of Medicinal Chemistry, 2011 , vol. 54, # 24 p. 8471 - 8489
反应条件
1: T=-90°C; 2: With water T=-90°C;
参考文献
Meana, Angela; Rodriguez, Justo F.; Sanz-Tejedor, M. Ascension; Garcia-Ruano, Jose L.
Synlett, 2003 , # 11 p. 1678 - 1682
反应条件
N-bromosuccinmide in acetonitrile Title compound not separated from byproducts;
参考文献
Synlett, , # 11 p. 1678 - 1682
反应条件
1: T=-90°C; 2: With water T=-90°C; Title compound not separated from byproducts;
参考文献
Synlett, , # 11 p. 1678 - 1682
反应条件
1: T=-90°C; 2: With water T=-90°C; Title compound not separated from byproducts;
参考文献
Synlett, , # 11 p. 1678 - 1682
反应条件
1: 88 percent / K2CO3 / acetone / Heating 2: 77 percent / KMnO4 / H2O / 3 h / 90 °C View Scheme
参考文献
LUMIPHORE, INC.; MAGDA, Darren; XU, Jide; BUTLIN, Nathaniel, G.
Patent: WO2014/78690 A1, 2014 ;
反应条件
potassium carbonate in acetone Heating;
参考文献
Ross Kelly; Lang, Fengrui
Tetrahedron Letters, 1995 , vol. 36, # 30 p. 5319 - 5322
Title/Abstract Full Text View citing articles Show Details
Kelly, T. Ross; Lang, Fengrui
Journal of Organic Chemistry, 1996 , vol. 61, # 14 p. 4623 - 4633
反应条件
1: 88 percent / K2CO3 / acetone / Heating 2: 77 percent / KMnO4 / H2O / 3 h / 90 °C 3: Et3N, DMAP / CH2Cl2 / 2 h / Ambient temperature 4: 98 percent / AlCl3, NaCl / 0.03 h / 150 °C View Scheme
参考文献
Kelly, T. Ross; Lang, Fengrui
Journal of Organic Chemistry, 1996 , vol. 61, # 14 p. 4623 - 4633
反应条件
1: 88 percent / K2CO3 / acetone / Heating 2: 77 percent / KMnO4 / H2O / 3 h / 90 °C 3: Et3N, DMAP / CH2Cl2 / 2 h / Ambient temperature 4: 93 percent / AlCl3 / CH2Cl2 / 48 h / Heating View Scheme
参考文献
LUMIPHORE, INC.; MAGDA, Darren; XU, Jide; BUTLIN, Nathaniel, G.
Patent: WO2014/78690 A1, 2014 ;
反应条件
1: 88 percent / K2CO3 / acetone / Heating 2: 77 percent / KMnO4 / H2O / 3 h / 90 °C 3: Et3N, DMAP / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
LUMIPHORE, INC.; MAGDA, Darren; XU, Jide; BUTLIN, Nathaniel, G.
Patent: WO2014/78690 A1, 2014 ;
