1-(4-硝基苯)-1H-咪唑合成路线 （共 18 条）
反应条件
N-(benzoyl)glycine; copper diacetate; caesium carbonate in N,N-dimethyl-formamide T=140°C; Ullmann coupling reaction; 30 h;
参考文献
Mao, Jincheng; Guo, Jun; Song, Hongliang; Ji, Shun-Jun
Tetrahedron, 2008 , vol. 64, # 7 p. 1383 - 1387
反应条件
8-Hydroxyquinoline 1-oxide; caesium carbonate; copper(I) bromide in dimethyl sulfoxide T=90°C; Ullmann coupling; 15 h; Inert atmosphereSealed tube; chemoselective reaction;
参考文献
Yang, Kai; Qiu, Yatao; Li, Zheng; Wang, Zhaoyang; Jiang, Sheng
Journal of Organic Chemistry, 2011 , vol. 76, # 9 p. 3151 - 3159
反应条件
copper(I) oxide; 1,10-phenanthroline; tetrabutyl ammonium fluoride T=140 - 145°C; 24 h;
参考文献
Tang, Bo-Xiao; Guo, Sheng-Mei; Zhang, Man-Bo; Li, Jin-Heng
Synthesis, 2008 , # 11 p. 1707 - 1716
反应条件
potassium carbonate in N,N-dimethyl-formamide T=70 - 80°C;
参考文献
Kitazaki, Tomoyuki; Ichikawa, Takashi; Tasaka, Akihiro; Hosono, Hiroshi; Matsushita, Yoshihiro; Hayashi, Ryogo; Okonogi, Kenji; Itoh, Katsumi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 12 p. 1935 - 1946
反应条件
copper(l) iodide; caesium carbonate; benzoyl-N'-phenylhydrazine in dimethyl sulfoxide T=120°C; Ullmann cross-coupling reaction; 1 h; Inert atmosphere;
参考文献
Li, Liuyi; Zhu, Lei; Chen, Dagui; Hu, Xuelei; Wang, Ruihu
European Journal of Organic Chemistry, 2011 , # 14 p. 2692 - 2696
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C; 8 h;
参考文献
Sreedhar; Arundhathi; Linga Reddy; Amarnath Reddy; Lakshmi Kantam
Synthesis, 2009 , # 15 art. no. P03909SS, p. 2517 - 2522
反应条件
2Na(1+)*CuC6H4(NCHC6H3OO3S)2(2-)=CuC6H4(NCHC6H3ONaO3S)2 in water T=100°C; 6 h;
参考文献
Wang, Lixia; Jiang, Zhaoqiong; Yu, Lintao; Li, Lili; Li, Zhengkai; Zhou, Xiangge
Chemistry Letters, 2010 , vol. 39, # 7 p. 764 - 765
反应条件
cesium fluoride in N,N-dimethyl-formamide T=60°C; 20 h; Inert atmosphere;
参考文献
Dehe, Daniel; Munstein, Isabel; Reis, Andreas; Thiel, Werner R.
Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1151 - 1154
反应条件
1: ethane-1,2-dial; 4-nitro-aniline in methanol; water T=20°C; 16 h; 2: formaldehyd With phosphoric acid; ammonium chloride in methanol; water Heating;
参考文献
Ahrens, Sebastian; Herdtweck, Eberhardt; Goutal, Sigrid; Strassner, Thomas
European Journal of Inorganic Chemistry, 2006 , # 6 p. 1268 - 1274
反应条件
1.1: aq. methanol / 16 h / 20 °C 2.1: aq. NH4Cl / methanol / 1 h / Heating 2.2: aq. H3PO4 / methanol / Heating View Scheme
参考文献
Synthesis, , # 17 p. 2661 - 2666
