3-苯基-1-氨基异喹啉合成路线 （共 25 条）
反应条件
1: 66 percent Spectr. / HBF4 / CH2Cl2; diethyl ether / 20 °C
2: 11 percent / NH3 / CH2Cl2 / 20 h
View Scheme
参考文献
Tovar, John D.; Swager, Timothy M.
Journal of Organic Chemistry, 1999 , vol. 64, # 17 p. 6499 - 6504
反应条件
1: 1.) tri-n-butylstannyl oxide / 1.) ethanol, reflux, 2 h, 2.) benzene, 10 h, reflux
2: methyltriphenylphosphonium iodide / hexamethylphosphoric acid triamide / 19 h / Ambient temperature
3: aq. sodium hydroxide / 2 h / Ambient temperature
4: 21 percent / ethanol / 3 h / Irradiation
View Scheme
参考文献
Casey, Michael; Moody, Christopher J.; Rees, Charles W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1933 - 1941
反应条件
1: methyltriphenylphosphonium iodide / hexamethylphosphoric acid triamide / 19 h / Ambient temperature
2: aq. sodium hydroxide / 2 h / Ambient temperature
3: 21 percent / ethanol / 3 h / Irradiation
View Scheme
参考文献
Casey, Michael; Moody, Christopher J.; Rees, Charles W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1933 - 1941
反应条件
1: 26 percent / methyltriphenylphosphonium iodide / hexamethylphosphoric acid triamide / 10 h
2: sodium ethoxide / ethanol / 0.75 h
3: 1.) tri-n-butylstannyl oxide / 1.) ethanol, reflux, 2 h, 2.) benzene, 10 h, reflux
4: methyltriphenylphosphonium iodide / hexamethylphosphoric acid triamide / 19 h / Ambient temperature
5: aq. sodium hydroxide / 2 h / Ambient temperature
6: 21 percent / ethanol / 3 h / Irradiation
View Scheme
参考文献
Casey, Michael; Moody, Christopher J.; Rees, Charles W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1933 - 1941
反应条件
1: sodium ethoxide / ethanol / 0.75 h
2: 1.) tri-n-butylstannyl oxide / 1.) ethanol, reflux, 2 h, 2.) benzene, 10 h, reflux
3: methyltriphenylphosphonium iodide / hexamethylphosphoric acid triamide / 19 h / Ambient temperature
4: aq. sodium hydroxide / 2 h / Ambient temperature
5: 21 percent / ethanol / 3 h / Irradiation
View Scheme
参考文献
Casey, Michael; Moody, Christopher J.; Rees, Charles W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1933 - 1941
反应条件
1: 1.) tri-n-butylstannyl oxide / 1.) ethanol, reflux, 2 h, 2.) benzene, 10 h, reflux
2: methyltriphenylphosphonium iodide / hexamethylphosphoric acid triamide / 19 h / Ambient temperature
3: aq. sodium hydroxide / 2 h / Ambient temperature
4: 21 percent / ethanol / 3 h / Irradiation
View Scheme
参考文献
Casey, Michael; Moody, Christopher J.; Rees, Charles W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1933 - 1941
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 3 h / 120 °C / |Microwave irradiation; |Inert atmosphere
2: ammonium acetate; NaAuCl4*2H2O; silver hexafluoroantimonate / acetonitrile / 20 h / 85 °C
View Scheme
参考文献
Long, Yuhua; She, Zhigang; Liu, Xiaochen; Chen, Yu
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2579 - 2588
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 3 h / 120 °C / |Microwave irradiation; |Inert atmosphere
2: ammonium acetate; NaAuCl4*2H2O; silver hexafluoroantimonate / acetonitrile / 20 h / 85 °C
View Scheme
参考文献
Long, Yuhua; She, Zhigang; Liu, Xiaochen; Chen, Yu
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2579 - 2588
反应条件
1: 1 h / 0 - 20 °C
2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 3 h / 120 °C / |Microwave irradiation; |Inert atmosphere
3: ammonium acetate; NaAuCl4*2H2O; silver hexafluoroantimonate / acetonitrile / 20 h / 85 °C
View Scheme
参考文献
Long, Yuhua; She, Zhigang; Liu, Xiaochen; Chen, Yu
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2579 - 2588
反应条件
1: 1 h / 0 - 20 °C
2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 3 h / 120 °C / |Microwave irradiation; |Inert atmosphere
3: ammonium acetate; NaAuCl4*2H2O; silver hexafluoroantimonate / acetonitrile / 20 h / 85 °C
View Scheme
参考文献
Long, Yuhua; She, Zhigang; Liu, Xiaochen; Chen, Yu
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2579 - 2588
