6,7-二氢噻吩并[3,2-C]吡啶-5(4H)-甲酸叔丁酯合成路线 （共 6 条）
反应条件
triethylamine in dichloromethane T=20°C; 2 h;
参考文献
WO2009/49028 A1, ;
Page/Page column 156 ;
WO 2009/049028 A1
反应条件
sodium hydroxide in 1,4-dioxane; water T=20°C;
参考文献
WO2006/47302 A1, ;
Page/Page column 74 ;
WO 2006/047302 A1
反应条件
triethylamine in chloroform
参考文献
US6015817 A1, ;
US 6015817 A
反应条件
triethylamine in dichloromethane
反应条件
1: With n-butyllithium; diisopropylamine in tetrahydrofuran T=-65 - -30°C; 2.5 h; 2: With boric acid trimethyl ester in tetrahydrofuran T=-65 - 10°C; 3: With water; ammonium chloride in tetrahydrofuran T=10°C; 0.5 h;
参考文献
TARGEGEN INC.
Patent: WO2009/26345 A1, 2009 ;
Location in patent: Page/Page column 56 ;
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
US6015817 A1, ;
US 6015817 A
