3-氨基-1,2-苯并异噻唑合成路线 （共 8 条）
反应条件
ammonia in formamide T=130°C; 0.75 h;
参考文献
Golec, Julian M. C.; Scrowston, Richard M.
Journal of Chemical Research, Miniprint, 1988 , # 1 p. 326 - 345
反应条件
hydrogenchloride in ethanol Heating;
参考文献
Justus Liebigs Annalen der Chemie, , p. 20 - 26
反应条件
1: NH2OH*HCl, NaOAc*3H2O / ethanol / Heating 2: aq. HCl / ethanol / Heating View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , p. 20 - 26
反应条件
1: 78 percent / Na2CO3 / dimethylformamide / Ambient temperature 2: benzene / 80 - 90 °C View Scheme
参考文献
Vicini; Amoretti; Chiavarini; Impicciatore
Farmaco, 1990 , vol. 45, # 9 p. 933 - 943
反应条件
1: benzo[d]isothiazol-3-amine; haloacetylchloride in N,N-dimethyl-formamide 2: dimethyl amine in benzene Heating;
参考文献
Geronikaki, Athina; Vicini, Paola; Dabarakis, Nikos; Lagunin, Alexey; Poroikov, Vladimir; Dearden, John; Modarresi, Hassan; Hewitt, Mark; Theophilidis, George
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 2 p. 473 - 481
反应条件
potassium carbonate in isopropyl alcohol Reflux;
参考文献
WO2013/14665 A1, ;
Page/Page column 21 ;
反应条件
thiophenol in toluene
T=80°C; 0.5 h;
参考文献
Boeshagen, Horst; Geiger, Walter
Liebigs Annalen der Chemie, 1982 , # 1 p. 14 - 27
反应条件
sodium acetate in diethyl ether
参考文献
Ciba-Geigy Corporation
Patent: US4698358 A1, 1987 ;
