1-(2-氨基-5-甲氧基苯基)-乙酮合成路线 （共 31 条）
反应条件
1: triethylamine / dichloromethane / 0 °C / Inert atmosphere
2: acetonitrile / 20 h / 20 °C / Inert atmosphere; UV-irradiation
View Scheme
参考文献
Guerrini, Giacomo; Taddei, Maurizio; Ponticelli, Fabio
Journal of Organic Chemistry, 2011 , vol. 76, # 18 p. 7597 - 7601
反应条件
1: acetic acid; potassium nitrate / 1.17 h / 60 °C / |Inert atmosphere
2: potassium carbonate / acetone / 20 °C / |Inert atmosphere
3: tin(ll) chloride / ethanol / 1 h / |Reflux; |Inert atmosphere
View Scheme
参考文献
Wang, Jingjing; Chen, Weiqiang; Zuo, Sujing; Liu, Lu; Zhang, Xinrui; Wang, Jianhui
Angewandte Chemie - International Edition, 2012 , vol. 51, # 49 p. 12334 - 12338
Angew. Chem., 2012 , vol. 124, # 49 p. 12500 - 12504,5
参考文献
Beer et al.
Journal of the Chemical Society, 1954 , p. 4139,4141
Full Text Show Details
Mentzer et al.
Bulletin de la Societe Chimique de France, 1950 , p. 555,560
参考文献
Beer et al.
Journal of the Chemical Society, 1954 , p. 4139,4141
Full Text Show Details
Mentzer et al.
Bulletin de la Societe Chimique de France, 1950 , p. 555,560
反应条件
1: petroleum ether
2: benzene
3: aqueous HCl
View Scheme
参考文献
Beer et al.
Journal of the Chemical Society, 1954 , p. 4139,4141
反应条件
1: benzene
2: aqueous HCl
View Scheme
参考文献
Beer et al.
Journal of the Chemical Society, 1954 , p. 4139,4141
反应条件
1: diethyl ether / beim Erhitzen des Reaktionsprodukts mit Essigsaeure und wenig H2SO4
2: iron-powder; aqueous acetic acid
View Scheme
参考文献
Osborn; Schofield
Journal of the Chemical Society, 1955 , p. 2100,2102
反应条件
N-chloro-succinimide in acetonitrile
T=55°C; 2 h;
参考文献
WYETH
Patent: WO2004/103973 A1, 2004 ;
Location in patent: Page 40-41 ;
WO 2004/103973 A1
反应条件
1: 77 percent / pyridine / CH2Cl2 / 1 h / Ambient temperature
2: TiCl3/C8K / 1,2-dimethoxy-ethane / 1 h / Heating
View Scheme
参考文献
Fuerstner, Alois; Jumbam, Denis N.; Seidel, Guenter
Chemische Berichte, 1994 , vol. 127, # 6 p. 1125 - 1130
反应条件
pyridine
T=10 - 20°C; 2 h;
参考文献
Boehringer Ingelheim International GmbH
Patent: US2007/37781 A1, 2007 ;
Location in patent: Page/Page column 35 ;
