1: 84 percent / p-toluenesulfonic acid, 4A molecular sieves / CH2Cl2 / 72 h / Heating 2: 1.) TMEDA, n-BuLi / 1.) Et2O, from -50 deg C to -5 deg C, 4 h, 2.) Et2O, RT, overnight 3: glacial acetic acid / 1 h / Heating View Scheme

1: 70 percent / acetic acid / 12 h / Heating 2: aq. NaOH / 0.08 h / Heating View Scheme

sodium hydroxide 0.0833333 h; Heating; Yield given;