2-氯-5-硝基-4-甲基吡啶合成路线 (共 31 条)
反应条件
1: N-ethoxycarbonyl-piperazine; 2-chloro-4-methyl-5-nitropyridine in ethanol
T=20°C; 72 h;
2: N,N-dimethyl-formamide dimethyl acetal in N,N-dimethyl-formamide
T=90°C; 72 h;
3: With potassium hydroxide; ethanol; water; hydrogen; acetic acid; triethylamine; palladium on activated carbon
more than 3 stages;
参考文献
Bang-Andersen, Benny; Larsen, Krestian; Mork, Niels
Patent: US2007/43058 A1, 2007 ;
Location in patent: Page/Page column 8 ;
US 20070043058 A1