hydrogenchloride; water in tetrahydrofuran T=20°C; 3 h;

1: pyridinium p-toluenesulfonate / 0 - 20 °C 2: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 14 h / 130 °C / Inert atmosphere 3: hydrogenchloride; water / tetrahydrofuran / 3 h / 20 °C View Scheme

cytochrome P450 BM3H F87A; dihydrogen peroxide in dimethyl sulfoxide T=20°C; pH=8.1; aq. phosphate bufferEnzymatic reaction;