2-溴-6-(吡咯烷-1-基)吡啶合成路线 （共 3 条）
反应条件
0.166667 h; Heating;
参考文献
UCB PHARMA S.A.; BUeRLI, Roland; HAUGHAN, Alan, Findlay; MACK, Stephen, Robert; PERRY, Benjamin, Garfield; RAPHY, Gilles; SAVILLE-STONES, Elizabeth, Anne
Patent: WO2010/52448 A2, 2010 ;
Location in patent: Page/Page column 42 ;
WO 2010/052448 A2
反应条件
potassium carbonate in ethyl acetate
反应条件
tert.-butyl lithium 1.) THF, pentane, -78 deg C, 1 h, 2.) THF, pentane, -78 deg C to rt, rt, overnight; Yield givenMultistep reaction;
参考文献
Sammakia, Tarek; Hurley, T. Brian
Journal of Organic Chemistry, 1999 , vol. 64, # 13 p. 4652 - 4664
